Read about what we've done, what we are doing and what's next.
The results of the largest study to date looking at genetic modifiers of the age of onset of dementia were recently published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. Cochran, along with collaborators from many other institutes, analyzed the genomes of 340 individuals from the Antioquia family as well as similar families from other studies to gain insight into the genetic landscape of age of disease onset.
HudsonAlpha Institute for Biotechnology’s Educational Outreach public education program gets a new look, just in time for the Institute’s 15th Anniversary.
Researchers at Duke University, HudsonAlpha Institute for Biotechnology, and Oak Ridge National Laboratory were part of a team that identified sex chromosomes in Sphagnum moss species. Since the sex of peat bog mosses alters carbon storage dynamics, this information could help protect Sphagnum and reduce the likelihood of peat bogs becoming major carbon sources.
HudsonAlpha internationally-renowned faculty members are committed to making impactful discoveries in genomics and genetics that improve health and create a more sustainable world.
Genetic architecture of morphologic variation
Greg Barsh, MD, PhD, Smith Family Chair in Genomics at the HudsonAlpha Institute for Biotechnology, studies the genetic mechanisms that underlie differences in individual appearance and that could give new insight into both basic biology and human disease.
Using genomics for crop improvement
Josh Clevenger, PhD, focuses on using genomics for crop improvement, especially crops in the southeast and Alabama.
Genomic approaches for the diagnosis and treatment of Alzheimer disease and other dementias.
Nick Cochran, PhD, focuses on genomic approaches for the diagnosis and treatment of Alzheimer disease and other dementias, with an end goal to improve the lives of those affected by neurodegenerative diseases.
Human Genetics and Genomics
Greg Cooper, PhD, researches the structures, functions and evolutionary histories of human genomes, with an emphasis on applying genomic approaches to study human disease.
Sara Cooper, PhD, focuses on combining metabolomics with genomics and applying that data to pancreatic and ovarian cancer.
Genomic resource development for plants
Jane Grimwood, PhD, co-directs the Genome Sequencing Center at HudsonAlpha, managing one of the few centers in the world that produces, analyzes, and interprets genomic data on economically important plant species to improve crop breeding and other agricultural practices. In 2022, she was named Loretta Purdy Spencer Chair in Genomics.
Plant Reproductive, Evolutionary, and Comparative Genomics
Alex Harkess , PhD studies plant reproductive, evolutionary, and comparative genomics. His research has focused on the evolution and function of small RNA pathways, the evolution of sex chromosomes in plants, and broad-scale comparative genomics.
PhD in Philosophy, Bowling Green State University
How genetics can address adoptees’ lack of family health history
Thomas May, PhD, is interested in the intersection of medicine; public health; and moral, social and political philosophy, with a special interest in autonomy and healthcare.
Genomic and genetic analysis of human traits and diseases.
Richard M. Myers, PhD, is Chief Scientific Officer, President Emeritus, ]M. A. Loya Chair in Genomics, and Faculty Investigator at the HudsonAlpha Institute for Biotechnology. The Myers lab focuses on using genomics tools and genetics to understand how changes in gene expression contribute to human health and disease, as well as to basic biological processes.
Whole genome sequencing and assembly, population genomics
Jeremy Schmutz co-directs the Genome Sequencing Center at HudsonAlpha, managing one of the few centers in the world that produces, analyzes and interprets genomic data on economically important plant and organism species to improve crop breeding and other agricultural practices.
Understanding the role of the rhizome in resource reallocation and perenniality.
Kankshita Swaminathan, PhD, studies the role of the rhizome in nutrient storage and reproduction in plants. She is interested in how perennial plants remobilize nutrients year after year.
Since opening its doors in 2008, HudsonAlpha has further secured its role as a global leader in biotechnology and genomic research. We’ve made discoveries in ALS, childhood genetic disorders and kidney cancer; expanded research in bipolar and schizophrenia and continued critical research in other devastating conditions, including cancer, Parkinson’s, lupus, multiple sclerosis and more.
Our agriscience team specializes in applying genomic techniques to understand how plants function in response to environmental stimuli. The HudsonAlpha Genome Sequencing Center is a global leader in providing de novo whole genome sequencing, assembly and analysis.
To leverage the synergy between discovery, education, medicine, and economic development in genomic sciences to improve the human condition around the globe.