Finding a trusted collaborator

Genetic testing can provide insights into disease risks and potential interventions, help individuals make more informed health decisions, and even target therapies that lead to better health outcomes. As genomic data becomes more integrated into health care and clinical decision making, there is a growing need for trusted collaborators to help guide everyone through the complexities of genomic health.

The HudsonAlpha Center for Genomic Health was formed to make precision medicine accessible to everyone. Our internationally recognized researchers, clinicians, analysts and informaticians give medical providers the means to help develop targeted treatment and prevention plans. We can provide you with the support you need to make precision medicine accessible to everyone. Health systems, self-insured employers and other population groups are already relying on the Center to bring the power of genomics to their groups.

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Precision medicine services for patients

The Center for Genomic Health is using the power of genomic medicine to deliver innovative solutions to individuals, health systems, physician networks, and more. We are continually refining and improving our genomic tests and tools to bring about proactive ways to detect disease. Improved health outcomes and pharmacogenomics solutions are just a few of the ways we are helping improve the quality of life for patients.

Diagnostic Sequencing

Clinical whole genome sequencing is designed to determine the entire genetic makeup of an individual by sequencing all of their DNA. Some changes in DNA sequence impact the development of symptoms and disease. Armed with this information, physicians can make diagnoses and choose appropriate treatments for patients. Learn more →

Adult Onset Actionable Disease Risk Screening

There are currently 73 genes that the ACMG recognizes as being associated with either a hereditary form of cardiovascular disease or cancer risk. An individual who has a change in one of these genes can work with their healthcare provider to make a plan for reducing disease risk through medical and lifestyle changes. Learn more →

Hereditary Cardiovascular Disease Risk Testing

Genetic testing for cardiovascular diseases may help patients and their families make well-informed decisions about managing their heart health. Cardiovascular conditions that are believed to have an inherited genetic component include cardiomyopathies, arrhythmias, and familial hypercholesterolemia. Learn more →

Hereditary Cancer Risk Testing

Cancer genetic testing looks for inherited gene mutations that might put a person at a higher risk of getting certain kinds of cancer. Information about your cancer risk can help inform early screening and prevention steps. Genetic screening of tumors can also improve patient outcomes by informing physicians of the appropriate treatment for that specific tumor. Learn more →

Pharmacogenomics

Pharmacogenomic testing provides information about many different genes and how they impact your body’s response to over one hundred drugs. For example, DNA variants can show that you need a higher or lower dose of a certain drug or that a different drug should be used instead. Pharmacogenomic testing can help healthcare providers make more informed decisions about your medications. Learn more →

Elective Insight Genomes

Any adult may elect to have their whole genome sequenced to gain a better understanding of current medical problems, gain information about future disease risk to guide preventative healthcare decisions, fill in gaps in family history, or provide information to relatives and future generations. Learn more →

Our genomic health collaborators

Genomic Testing

Clinical genome sequencing could benefit patients whose clinical presentations have defied diagnosis, or for whom a diagnosis doesn’t completely “fit” the symptoms or manifestation of the disease, and for which the cause appears genetic in origin. These patients will typically have seen a number of specialists and current therapies are unsuccessful in alleviating symptoms or providing a significant improvement in health.

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Genetic Counseling

Genetic counseling is the process of helping individuals understand how genetic information relates to human health and disease risk. HudsonAlpha’s genetic counselors provide a critical service to individuals and families undergoing genetic testing by investigating the family history and interpreting the information gathered from both risk assessments and the genetic testing process itself.

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Medical Provider Education and Decision Support

Genome Gateway is an online tool that is optimized to give providers genomic test options, results, and actionable next steps, while helping provide clinical decision support. Programs like Genomics in Your Practice help educate medical providers to understand how the science of genomics can impact their patients and get them thinking genomics could help reveal underlying causes of a disease.

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Rare and Undiagnosed Disease Clinic

The Smith Family Clinic for Genomic Medicine, LLC., was established to diagnose patients with undiagnosed and misdiagnosed diseases. Patients or participants may have a medical condition that has eluded diagnosis despite considerable effort, and you believe that this condition may have an underlying genetic cause. In some cases, genetic testing may be a useful tool to find the answer.

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Health Care Delivery Systems

The HudsonAlpha Software Engineering team both develops and makes use of applications to analyze genomic and clinical datasets to support the interpretation of genomic data. The team provides software and informatics support and tools for clinical genomics applications such as those used at the HudsonAlpha Clinical Services Lab, LLC., to help patients and their physicians to find answers to unknown or misdiagnosed diseases.

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Clinical and Community Research Programs

Information is Power Initiative

HudsonAlpha established the Information is Power initiative to help the more than 30,000 Alabama men and women who will be diagnosed with cancer each year. The simple saliva test screens for the well-known BRCA1 and BRCA2 genes, as well as several dozen other genes linked to breast, ovarian, colon, prostate, pancreatic, and other cancers.

Alabama Genomic Health Initiative-AGHI

The Alabama Genomic Health Initiative (AGHI) is a partnership between HudsonAlpha and UAB-Medicine to provide genomic testing, interpretation, and counseling free of charge to residents in each of Alabama’s 67 counties. The AGHI also includes a major focus on research, through which data from test results will be used to advance scientific understanding of the role that genes play in health and disease.

SouthSeq, BabySeq & CSER

SouthSeq is a NIH-funded research study looking at how a new kind of genetic test, called whole genome sequencing, can be used to try to find the reason for medical problems among newborns in a neonatal intensive care unit (NICU).

BabySeq seeks to implement whole genome sequencing as routine screening in a diverse cohort of healthy infants

The Clinical Sequencing Exploratory Research (CSER) program is a consortium of many minds working together to advance human health through the science and study of genomics. Formed by the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), CSER brings together scientists, scholars, ethicists, clinicians, bioinformaticians, and patients to drive projects that innovate how genomic sequencing is applied in clinical care.

Meet the Director

Devin Absher, PhD, serves as the Director of the HudsonAlpha Center for Genomic Health, which includes The HudsonAlpha Health Alliance, the HudsonAlpha Clinical Services Lab, The Smith Family Clinic for Genomic Medicine, and a number of genomic health researchers.
Absher is also a HudsonAlpha Faculty Investigator. His current research focuses on application of genomics to complex diseases and traits, including genome-wide association studies and epigenetic studies.

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Collaborate with us

Genetics and genomics are at the center of our mission at HudsonAlpha. From day one, our vision has been to leverage the synergy in human and plant genomic science to improve the human condition around the globe. Whether you are looking for a sequencing partner, a research collaboration or access to genomic health solutions for your patients or employees, HudsonAlpha is able to deliver innovative solutions to solve complex problems. The Center for Genomic Health is just one of the ways to collaborate at HudsonAlpha.

HudsonAlpha Institute for Biotechnology
CENTER FOR GENOMIC HEALTH
601 Genome Way
Huntsville, AL 35806
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