From DNA to Decision
HudsonAlpha Scientific Services
Unlock the Power of Genomics with HudsonAlpha
HudsonAlpha Institute for Biotechnology offers comprehensive, full-service genomic solutions, providing researchers, clinicians, and industry leaders with high-quality genomic data that drives innovation in agriculture, human health, and beyond. From DNA/RNA extraction and sequencing to advanced bioinformatics analysis, our DNA-to-decision approach ensures actionable insights from every sample.
End-to-End Genomic Services
HudsonAlpha provides complete genomic services for humans, plants, animals, bacteria, and viruses, including:
Whole Genome Sequencing (WGS)
High-quality short-read sequencing using Illumina NovaSeq X and long-read sequencing with PacBio Revio HiFi technology.
RNA Sequencing (RNA-seq and Kinnex)
Comprehensive transcriptomics to quantify and compare gene expression, annotate transcript isoforms, and perform functional analysis of mutants and edited samples across diverse organisms.
Genotyping & Variant Analysis
Accurate discovery and detection of polymorphisms, including SNPs and various structural variants, for pangenomic research, large population cohorts, and breeding applications.
De novo Genome Assembly
All-inclusive, high-accuracy service to extract, sequence, and build novel, highest quality genomes for any species, be it new, large, or complex.
Specialized Services
Advanced bioinformatics to investigate specific research areas, including sex chromosome analysis and Khufu trait mapping analysis.
Our services are designed to support precision breeding, molecular genetics, functional genomics, and translational research.
PacBio Grade Molecular Weight DNA prep
Illumina Grade DNA prep
DNAase treatment of RNA
CCSExpress Library (HiFi) Indexed
High throughput HiFi library construction
Isoseq Express
Kinnex Library
PacBio 16S Library
Illumina PCRfree Library
Illumina nano amplified Library
Dovetail OmniC library
Low-pass sequencing library plates
Custom targeted enrichment sequencing
Revio SMRT sequencing
Illumina NovaSeq X sequencing
Variant calling on RUO human data
Genome Assembly & Annotation
PacBio data analysis
Genotyping
Genome editing and transgenic support
Custom consulting and analysis services
Agriculture & Crop Improvement Services
HudsonAlpha is a leader in agricultural genomics, helping partners achieve improved crop traits, biodiversity preservation, and pangenome analysis:
Trait Mapping with Khufu
Efficiently identify functional SNPs and QTLs to accelerate marker-assisted selection and breeding programs.
Sex Determination Analysis
Detailed genomic characterization of sex-determining loci and chromosomes in various species, including both plants and animals, to support both basic research and breeding applications.
Pangenome Assemblies
Construction of comprehensive multi-reference pangenomes that capture and enable better utilization of the full genetic diversity across plant and animal species.
Biodiversity & Conservation
Application of genomics tools to enhance sustainability and preserve genetic diversity.
Our collaborative efforts span seed repositories, agricultural research institutes, and food processors, translating genomic insights into practical applications for yield improvement, disease resistance, stress tolerance, and other benefits.
Human RUO Services
The HudsonAlpha Genome Sequencing Center, part of the HudsonAlpha Institute for Biotechnology, offers comprehensive human long-read genome sequencing using the advanced PacBio Revio platform. As a PacBio Certified Service Provider and trusted NIH collaborator, we provide full-service sequencing, from DNA extraction through advanced analysis, designed to uncover complex genomic variation with unmatched resolution.
Our Revio-based HiFi sequencing services are ideal for uncovering structural variants, repeat expansions, haplotypes, and other genomic elements that can be overlooked by short-read platforms.
Whether your research focuses on rare disease, pediatric cancer, or population-scale genomics, HudsonAlpha delivers publication-ready data and scientific partnership.
Advanced Long-Read Sequencing with PacBio Revio
HudsonAlpha provides PacBio Revio long-read sequencing, enabling detailed exploration of complex genomes. Key Advantages:
High-Fidelity Long Reads
Exceptional accuracy, ideal for complex genomic regions.
Structural Variant Detection
Detect large insertions, deletions, and complex rearrangements.
De novo Assembly Excellence
Generate complete, contiguous genome assemblies for novel or complex organisms.
Scalable Workflow
Efficient for both small and large projects.
PacBio Revio complements short-read sequencing, creating a comprehensive toolkit for genome assembly, variant discovery, and functional genomics.
Sequencing Excellence with Illumina NovaSeq X
The NovaSeq X enables rapid and reliable generation of short-read genomic data, supporting both fundamental research and applied genomics.
High Throughput
Accelerated sequencing for large sample volumes.
Cost Efficiency
Reduced per-sample costs without compromising quality.
Scalability
Flexible solutions for research, breeding programs, and clinical studies.
Why Choose HudsonAlpha Scientific Services?
Expertise
A team of seasoned scientists and bioinformaticians dedicated to your success.
Innovation
Access to cutting-edge sequencing technologies and analysis tools.
Collaboration
Dedicated support to meet client-specific research and breeding goals.
Quality
Rigorous quality control ensures reliable and reproducible genomic data.
Get Started with HudsonAlpha
Turn your genomic data into actionable insights. Contact HudsonAlpha today to discuss your genomics projects.
HudsonAlpha Institute for Biotechnology: Advancing science, improving lives through cutting-edge genomics.
Contact Information
Address: 601 Genome Way, Huntsville, AL 35806