NOTICE OF SIGNIFICANT FINANCIAL INTEREST:

HudsonAlpha Institute for Biotechnology (the “Institute”) has determined that key personnel on a PHS-funded research project has a Significant Financial Interest (“SFI”) that the Institute has determined is related to the PHS-funded research. Information regarding the SFI is available in writing within five business days of the receipt of a request. Requests for information regarding this SFI should be in writing and directed to: HudsonAlpha Institute for Biotechnology, Attn: Office of Legal Affairs & Compliance, 601 Genome Way, Huntsville, AL 35806