Genome Sequencing Center
Jane Grimwood, Ph.D. (read bio)
Faculty Investigator
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Jeremy Schmutz (read bio)
Faculty Investigator
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Research interests
- Genome improvement and finishing of eukaryotic organisms
- Cloning systems
- Host/pathogen interactions at the cellular and the genomic levels
- Comparative sequence analysis
- Whole genome sequencing and assembly
- Constructing complex data collection and analysis systems in order to answer specific scientific questions
- Genomic changes in populations in response to selective environmental pressures
- Understanding the structural organization of genomes through comparative analysis of the genomes of related species
View the Genome Sequencing Center website
Why we have plenty of fish in the sea
HUNTSVILLE, Ala. -- New work from the HudsonAlpha Institute for Biotechnology, with collaborators at Stanford University and five other groups, has pinpointed evolution in action.
By determining genomic sequence from many groups of stickleback fish, the scientists were able to show specific genomic changes leading to the ability of different fish populations to adapt to new environments. “We were pleased with the ability of genomics to show us what molecular changes are important in evolutionary processes,” said Richard Myers, Ph.D., president and director of HudsonAlpha.
How can the fuzz that grows on the shells of hermit crabs have any relationship to human health? Well, the HudsonAlpha Genome Sequencing Center recently generated the finished genomic sequence for research conducted by Yale scientists studying Hydractinia symbiolongicarpus (the distinctive white fuzz growing on the top of hermit crab shells). The Yale scientists subsequently identified a candidate allorecognition gene that could eventually lead to better understanding of the human immune system. Allorecognition is the ability of an individual organism to distinguish its own tissues from those of another.
