Genome Sequencing Center
Jane Grimwood, Ph.D. (read bio)
Faculty Investigator
Contact
Jeremy Schmutz (read bio)
Faculty Investigator
Contact
Research interests
- Genome improvement and finishing of eukaryotic organisms
- Cloning systems
- Host/pathogen interactions at the cellular and the genomic levels
- Comparative sequence analysis
- Whole genome sequencing and assembly
- Constructing complex data collection and analysis systems in order to answer specific scientific questions
- Genomic changes in populations in response to selective environmental pressures
- Understanding the structural organization of genomes through comparative analysis of the genomes of related species
How can the fuzz that grows on the shells of hermit crabs have any relationship to human health? Well, the HudsonAlpha Genome Sequencing Center recently generated the finished genomic sequence for research conducted by Yale scientists studying Hydractinia symbiolongicarpus (the distinctive white fuzz growing on the top of hermit crab shells). The Yale scientists subsequently identified a candidate allorecognition gene that could eventually lead to better understanding of the human immune system. Allorecognition is the ability of an individual organism to distinguish its own tissues from those of another.
