Barsh Lab

Greg Barsh, M.D., Ph.D. (read bio)

Faculty Investigator/Mark C. Smith Investigator

Dr. BarshResearch areas:

  • Color variation to explorefundamental aspects of gene action, development, complex traits, evolution
  • Forward genetic analysis of skin color and pigment-type switching in laboratory mice
  • Biology of melanocortin signaling
  • Genetic architecture of human pigmentary variation
  • Biology and evolution of color patterns in mammals

Information for the science community can be found by going to the personal webpage Barsh Lab.

NPR features HudsonAlpha's involvement in cat coloration study

News Outlet: 
Date published: 
September 20, 2012


At this point it's just an interesting hypothesis, but it's possible that understanding cat coloration could help scientists understand resistance to infectious diseases.
Here's the connection. Stephen O'Brien and colleagues at a variety of institutions including the HudsonAlpha Institute for Biotechnology in Huntsville, Ala., and Stanford University in California have worked out some of the genetic pathways that explain why "some cats are spotted, some cats have stripes, some cats have what we call blotches, and other cats don't have any of that, they just have a black or a lion-like color," says O'Brien.

How the cat got his blotches

As any cat lover knows, distinct patterns of dark and light hair color are apparent not only in house cats but also in their wild relatives, from cheetahs to tigers to snow leopards. Researchers at the HudsonAlpha Institute for Biotechnology and Stanford University, along with colleagues around the world, today reported new genetic findings that help to understand the molecular basis of these patterns in all felines.

New research grant to study childhood genetic disorders featured in local media

News Outlet: 
The Huntsville Times,
Date published: 
July 22, 2013

HUNTSVILLE, Ala. - DNA data from hundreds of North Alabama children and their parents will soon be part of a major new genetic study of childhood diseases led by Huntsville's HudsonAlpha Institute for Biotechnology and including the University of Alabama in Birmingham. The National Institutes of Health announced a $7.6 million research grant Tuesday to the non-profit institute for the study.

HudsonAlpha adds two new investigators

Collaborative environment unique to the institute attracts new scientists

Dr. Richard Myers, president and director of the HudsonAlpha Institute for Biotechnology, is pleased to announce the addition of Faculty Investigators Drs. Greg Barsh and Shawn Levy. “With Dr. Barsh and Dr. Levy, the institute is gaining a remarkable combination of expertise in genetics and genomics research, particularly relating to human diseases,” said Myers.

Both scientists were attracted by the unique infrastructure afforded by HudsonAlpha’s three-fold mission of genomics research, economic development and educational outreach.

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